Xanthohumol inhibits angiogenic vessels but not stable vessels

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Evidence for the Effects of Xanthohumol in Disrupting Angiogenic, but not Stable Vessels

Angiogenesis is a complex multistep process that comprises proliferation, migration, and anastomosis of endothelial cells, followed by stabilization of the newly formed vessel through the attachment of support cells. This process is imbalanced in a large number of disorders, including cardiovascular disease, diabetes and cancer. Evidence indicates that xanthohumol (XN), a prenylated chalcone pr...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2007

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.21.6.a1095-a